A one-year planning grant was awarded by The Andrew W. Mellon Foundation to study the feasibility of establishing Centers of Excellence (CoEs). This study recognizes CoEs as a means to provide new information services that libraries are increasingly expected to deliver in order to meet the needs of twenty-first century research, teaching, and learning. The study explored the characteristics of CoEs, what makes them successful, and the challenges commonly faced by centers. Study findings were presented during this breakout session, and preliminary recommendations for following a Centers of Excellence model in developing and delivering information services were also discussed.